Empirical ways to identify novel Bedaquiline resistance mutations in AtpE

Clinical resistance against Bedaquiline, the first new anti-tuberculosis compound with a novel mechanism of action in over 40 years, has already been detected in Mycobacterium tuberculosis. As a new drug, however, there is currently insufficient clinical data to facilitate reliable and timely identi...

Descripción completa

Detalles Bibliográficos
Autores principales: Karmakar, Malancha, Rodrigues, Carlos H. M., Holt, Kathryn E., Dunstan, Sarah J., Denholm, Justin, Ascher, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541270/
https://www.ncbi.nlm.nih.gov/pubmed/31141524
http://dx.doi.org/10.1371/journal.pone.0217169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541270/
https://www.ncbi.nlm.nih.gov/pubmed/31141524
http://dx.doi.org/10.1371/journal.pone.0217169

Ejemplares similares