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Evolution of major histocompatibility complex gene copy number

MHC genes, which code for proteins responsible for presenting pathogen-derived antigens to the host immune system, show remarkable copy-number variation both between and within species. However, the evolutionary forces driving this variation are poorly understood. Here, we use computer simulations t...

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Detalles Bibliográficos
Autores principales: Bentkowski, Piotr, Radwan, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541284/
https://www.ncbi.nlm.nih.gov/pubmed/31095555
http://dx.doi.org/10.1371/journal.pcbi.1007015