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An integrative approach identifies direct targets of the late viral transcription complex and an expanded promoter recognition motif in Kaposi’s sarcoma-associated herpesvirus

The structural proteins of DNA viruses are generally encoded by late genes, whose expression relies on recruitment of the host transcriptional machinery only after the onset of viral genome replication. β and γ-herpesviruses encode a unique six-member viral pre-initiation complex (vPIC) for this pur...

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Detalles Bibliográficos
Autores principales: Nandakumar, Divya, Glaunsinger, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541308/
https://www.ncbi.nlm.nih.gov/pubmed/31095645
http://dx.doi.org/10.1371/journal.ppat.1007774