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A three-component, Zn(OTf)(2)-mediated entry into trisubstituted 2-aminoimidazoles

A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)(2)-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported base-promoted unimolecular cyclization of propargylu...

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Detalles Bibliográficos
Autores principales: Lukin, Alexei, Bakholdina, Anna, Kryukova, Anna, Sapegin, Alexander, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541334/
https://www.ncbi.nlm.nih.gov/pubmed/31164943
http://dx.doi.org/10.3762/bjoc.15.103