Cargando…

The association of elevated maternal genetic risk scores for hypertension, type 2 diabetes and obesity and having a child with a congenital heart defect

BACKGROUND: Maternal hypertension, type 2 diabetes (T2D) and obesity are associated with an increased risk of having offspring with conotruncal heart defects (CTDs). Prior studies have identified sets of single nucleotide polymorphisms (SNPs) that are associated with risk for each of these three adu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaplinski, Michelle, Taylor, Deanne, Mitchell, Laura E., Hammond, Dorothy A., Goldmuntz, Elizabeth, Agopian, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541344/
https://www.ncbi.nlm.nih.gov/pubmed/31141530
http://dx.doi.org/10.1371/journal.pone.0216477