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Lambda interferons come to light: dual function cytokines mediating antiviral immunity and damage control

Lambda interferons (IFNλs, type III IFNs or interleukins-28/29) were described fifteen years ago as novel cytokines sharing structural and functional homology with IL-10 and type I IFNs, respectively. IFNλs engage a unique receptor complex comprising IFNLR1 and IL10R2, nevertheless they share signal...

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Detalles Bibliográficos
Autores principales: Andreakos, Evangelos, Zanoni, Ivan, Galani, Ioanna E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541392/
https://www.ncbi.nlm.nih.gov/pubmed/30399529
http://dx.doi.org/10.1016/j.coi.2018.10.007