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REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice
PURPOSE: The present study was designed to evaluate the role of the stress response protein REDD1 in diabetes-induced oxidative stress and retinal pathology. METHODS: Wild-type and REDD1-deficient mice were administered streptozotocin to induce diabetes. Some mice received the antioxidant N-acetyl-l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541429/ https://www.ncbi.nlm.nih.gov/pubmed/31141608 http://dx.doi.org/10.1167/iovs.19-26606 |