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REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice

PURPOSE: The present study was designed to evaluate the role of the stress response protein REDD1 in diabetes-induced oxidative stress and retinal pathology. METHODS: Wild-type and REDD1-deficient mice were administered streptozotocin to induce diabetes. Some mice received the antioxidant N-acetyl-l...

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Detalles Bibliográficos
Autores principales: Miller, William P., Toro, Allyson L., Barber, Alistair J., Dennis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541429/
https://www.ncbi.nlm.nih.gov/pubmed/31141608
http://dx.doi.org/10.1167/iovs.19-26606