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REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice

PURPOSE: The present study was designed to evaluate the role of the stress response protein REDD1 in diabetes-induced oxidative stress and retinal pathology. METHODS: Wild-type and REDD1-deficient mice were administered streptozotocin to induce diabetes. Some mice received the antioxidant N-acetyl-l...

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Detalles Bibliográficos
Autores principales:	Miller, William P., Toro, Allyson L., Barber, Alistair J., Dennis, Michael D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541429/ https://www.ncbi.nlm.nih.gov/pubmed/31141608 http://dx.doi.org/10.1167/iovs.19-26606

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