Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2

Imprinted X-inactivation silences genes exclusively on the paternally-inherited X-chromosome and is a paradigm of transgenerational epigenetic inheritance in mammals. Here, we test the role of maternal vs. zygotic Polycomb repressive complex 2 (PRC2) protein EED in orchestrating imprinted X-inactiva...

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Detalles Bibliográficos
Autores principales: Harris, Clair, Cloutier, Marissa, Trotter, Megan, Hinten, Michael, Gayen, Srimonta, Du, Zhenhai, Xie, Wei, Kalantry, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541438/
https://www.ncbi.nlm.nih.gov/pubmed/30938678
http://dx.doi.org/10.7554/eLife.44258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541438/
https://www.ncbi.nlm.nih.gov/pubmed/30938678
http://dx.doi.org/10.7554/eLife.44258

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