Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences

BACKGROUND: Although cell lines are an essential resource for studying cancer biology, many are of unknown ancestral origin, and their use may not be optimal for evaluating the biology of all patient populations. METHODS: An admixture analysis was performed using genome‐wide chip data from the Catal...

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Detalles Bibliográficos
Autores principales: Kessler, Michael D., Bateman, Nicholas W., Conrads, Thomas P., Maxwell, George L., Dunning Hotopp, Julie C., O’Connor, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541501/
https://www.ncbi.nlm.nih.gov/pubmed/30865299
http://dx.doi.org/10.1002/cncr.32020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541501/
https://www.ncbi.nlm.nih.gov/pubmed/30865299
http://dx.doi.org/10.1002/cncr.32020

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