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Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation

Accelerated glucose metabolism is critical in hepatocarcinogenesis, but the utilities of different glucose transporter inhibitors in treating hepatocellular carcinoma (HCC) remain largely uncharacterized. In this study, we examined a collection of glucose transporter inhibitors and found differentia...

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Detalles Bibliográficos
Autores principales: Hung, Man-Hsin, Chen, Yao-Li, Chen, Li-Ju, Chu, Pei-Yi, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Shih, Chih-Ting, Chao, Tzu-I, Huang, Chao-Yuan, Chen, Kuen-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541593/
https://www.ncbi.nlm.nih.gov/pubmed/31142735
http://dx.doi.org/10.1038/s41419-019-1646-6