Cargando…
Canagliflozin inhibits growth of hepatocellular carcinoma via blocking glucose-influx-induced β-catenin activation
Accelerated glucose metabolism is critical in hepatocarcinogenesis, but the utilities of different glucose transporter inhibitors in treating hepatocellular carcinoma (HCC) remain largely uncharacterized. In this study, we examined a collection of glucose transporter inhibitors and found differentia...
Autores principales: | Hung, Man-Hsin, Chen, Yao-Li, Chen, Li-Ju, Chu, Pei-Yi, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Shih, Chih-Ting, Chao, Tzu-I, Huang, Chao-Yuan, Chen, Kuen-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541593/ https://www.ncbi.nlm.nih.gov/pubmed/31142735 http://dx.doi.org/10.1038/s41419-019-1646-6 |
Ejemplares similares
-
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6‐independent manner
por: Hsieh, Feng‐Shu, et al.
Publicado: (2017) -
Effects of canagliflozin on cardiac remodeling and hemodynamic parameters in patients with type 2 diabetes mellitus
por: Kuo, Hsiao-Huai, et al.
Publicado: (2023) -
Cardiorenal protective effects of canagliflozin in CREDENCE according to glucose lowering
por: Charytan, David M, et al.
Publicado: (2023) -
Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets
por: Jing, Muhan, et al.
Publicado: (2021) -
Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction
por: Huang, Rui, et al.
Publicado: (2021)