The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry

The UbiX-UbiD enzymes are widespread in microbes, acting in concert to decarboxylate alpha-beta unsaturated carboxylic acids using a highly modified flavin cofactor, prenylated FMN (prFMN). UbiX serves as the flavin prenyltransferase, extending the isoalloxazine ring system with a fourth non-aromati...

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Detalles Bibliográficos
Autores principales: Marshall, Stephen A., Payne, Karl A. P., Fisher, Karl, White, Mark D., Ní Cheallaigh, Aisling, Balaikaite, Arune, Rigby, Stephen E. J., Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541611/
https://www.ncbi.nlm.nih.gov/pubmed/31142738
http://dx.doi.org/10.1038/s41467-019-10220-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541611/
https://www.ncbi.nlm.nih.gov/pubmed/31142738
http://dx.doi.org/10.1038/s41467-019-10220-1

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