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Immunostimulatory functions of adoptively transferred MDSCs in experimental blunt chest trauma

Myeloid-derived suppressor cells (MDSCs) expand during inflammation and exhibit immunomodulatory functions on innate and adaptive immunity. However, their impact on trauma-induced immune responses, characterized by an early pro-inflammatory phase and dysregulated adaptive immunity involving lymphocy...

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Detalles Bibliográficos
Autores principales: Kustermann, Monika, Klingspor, Malena, Huber-Lang, Markus, Debatin, Klaus-Michael, Strauss, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541619/
https://www.ncbi.nlm.nih.gov/pubmed/31142770
http://dx.doi.org/10.1038/s41598-019-44419-5