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RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme

Glioblastoma multiforme (GBM) is a primary brain tumor characterized by extensive necrosis and immunosuppressive inflammation. The mechanisms by which this inflammation develops and persists in GBM remain elusive. We identified two cytokines interleukin-1β (IL-1) and oncostatin M (OSM) that strongly...

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Detalles Bibliográficos
Autores principales: Waters, Michael R., Gupta, Angela S., Mockenhaupt, Karli, Brown, LaShardai N., Biswas, Debolina D., Kordula, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541631/
https://www.ncbi.nlm.nih.gov/pubmed/31142741
http://dx.doi.org/10.1038/s41389-019-0146-y