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RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme
Glioblastoma multiforme (GBM) is a primary brain tumor characterized by extensive necrosis and immunosuppressive inflammation. The mechanisms by which this inflammation develops and persists in GBM remain elusive. We identified two cytokines interleukin-1β (IL-1) and oncostatin M (OSM) that strongly...
Autores principales: | Waters, Michael R., Gupta, Angela S., Mockenhaupt, Karli, Brown, LaShardai N., Biswas, Debolina D., Kordula, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541631/ https://www.ncbi.nlm.nih.gov/pubmed/31142741 http://dx.doi.org/10.1038/s41389-019-0146-y |
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