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Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy

Schwann cells ensure efficient nerve impulse conduction in the peripheral nervous system. Their development is accompanied by defined chromatin changes, including variant histone deposition and redistribution. To study the importance of variant histones for Schwann cell development, we altered their...

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Detalles Bibliográficos
Autores principales: Fröb, Franziska, Sock, Elisabeth, Tamm, Ernst. R., Saur, Anna-Lena, Hillgärtner, Simone, Williams, Trevor J., Fujii, Toshihiro, Fukunaga, Rikiro, Wegner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541636/
https://www.ncbi.nlm.nih.gov/pubmed/31142747
http://dx.doi.org/10.1038/s41467-019-10287-w