Anephrogenic phenotype induced by SALL1 gene knockout in pigs

To combat organ shortage in transplantation medicine, a novel strategy has been proposed to generate human organs from exogenous pluripotent stem cells utilizing the developmental mechanisms of pig embryos/foetuses. Genetically modified pigs missing specific organs are key elements in this strategy....

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Detalles Bibliográficos
Autores principales: Watanabe, Masahito, Nakano, Kazuaki, Uchikura, Ayuko, Matsunari, Hitomi, Yashima, Sayaka, Umeyama, Kazuhiro, Takayanagi, Shuko, Sakuma, Tetsushi, Yamamoto, Takashi, Morita, Sumiyo, Horii, Takuro, Hatada, Izuho, Nishinakamura, Ryuichi, Nakauchi, Hiromitsu, Nagashima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541644/
https://www.ncbi.nlm.nih.gov/pubmed/31142767
http://dx.doi.org/10.1038/s41598-019-44387-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541644/
https://www.ncbi.nlm.nih.gov/pubmed/31142767
http://dx.doi.org/10.1038/s41598-019-44387-w

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