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Peli1 controls the survival of dopaminergic neurons through modulating microglia-mediated neuroinflammation

Chronic neuroinflammation is known to contributes to the toxicity of neurodegeneration of Parkinson’s disease (PD). However, the molecular and cellular mechanisms controlling inflammatory responses in the central nervous system remain poorly understood. Here we found that a E3 ubiquitin ligase Peli1...

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Detalles Bibliográficos
Autores principales: Dai, Dongfang, Yuan, Jia, Wang, Yan, Xu, Jing, Mao, Chaoming, Xiao, Yichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541652/
https://www.ncbi.nlm.nih.gov/pubmed/31142803
http://dx.doi.org/10.1038/s41598-019-44573-w