Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. The glutamine antagonist, 6-diazo-5...

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Detalles Bibliográficos
Autores principales: Mukherjee, Purna, Augur, Zachary M., Li, Mingyi, Hill, Collin, Greenwood, Bennett, Domin, Marek A., Kondakci, Gramoz, Narain, Niven R., Kiebish, Michael A., Bronson, Roderick T., Arismendi-Morillo, Gabriel, Chinopoulos, Christos, Seyfried, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541653/
https://www.ncbi.nlm.nih.gov/pubmed/31149644
http://dx.doi.org/10.1038/s42003-019-0455-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541653/
https://www.ncbi.nlm.nih.gov/pubmed/31149644
http://dx.doi.org/10.1038/s42003-019-0455-x

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