Runx2 stimulates neoangiogenesis through the Runt domain in melanoma

Runx2 is a transcription factor involved in melanoma cell migration and proliferation. Here, we extended the analysis of Runt domain of Runx2 in melanoma cells to deepen understanding of the underlying mechanisms. By the CRISPR/Cas9 system we generated the Runt KO melanoma cells 3G8. Interestingly,...

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Detalles Bibliográficos
Autores principales: Cecconi, Daniela, Brandi, Jessica, Manfredi, Marcello, Serena, Michela, Carbonare, Luca Dalle, Deiana, Michela, Cheri, Samuele, Parolini, Francesca, Gandini, Alberto, Marchetto, Giulia, Innamorati, Giulio, Avanzi, Francesco, Antoniazzi, Franco, Marengo, Emilio, Tiso, Natascia, Mottes, Monica, Zipeto, Donato, Valenti, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541657/
https://www.ncbi.nlm.nih.gov/pubmed/31142788
http://dx.doi.org/10.1038/s41598-019-44552-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541657/
https://www.ncbi.nlm.nih.gov/pubmed/31142788
http://dx.doi.org/10.1038/s41598-019-44552-1

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