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Neonatal thrombocytopenia: Thrombin generation in presence of reduced platelet counts and effects of rFVIIa in cord blood

Healthy neonates exhibit a well-functioning haemostatic system despite peculiarities regarding composition of clotting factors and inhibitors as well as impaired platelet aggregation. Thrombocytopenia and severe bleeding events are feared in sick infants. Recombinant factor VIIa (rFVIIa) is a haemos...

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Detalles Bibliográficos
Autores principales: Haidl, Harald, Pohl, Sina, Leschnik, Bettina, Gallistl, Siegfried, Muntean, Wolfgang, Schlagenhauf, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541708/
https://www.ncbi.nlm.nih.gov/pubmed/31142810
http://dx.doi.org/10.1038/s41598-019-44199-y