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A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy
Clinically, both percutaneous and surgical approaches to deliver viral vectors to the heart either have resulted in therapeutically inadequate levels of transgene expression or have raised safety concerns associated with extra-cardiac delivery. Recent developments in the field of normothermic ex viv...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541710/ https://www.ncbi.nlm.nih.gov/pubmed/31142753 http://dx.doi.org/10.1038/s41598-019-43737-y |