A normothermic ex vivo organ perfusion delivery method for cardiac transplantation gene therapy

Clinically, both percutaneous and surgical approaches to deliver viral vectors to the heart either have resulted in therapeutically inadequate levels of transgene expression or have raised safety concerns associated with extra-cardiac delivery. Recent developments in the field of normothermic ex viv...

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Detalles Bibliográficos
Autores principales: Bishawi, Muath, Roan, Jun-Neng, Milano, Carmelo A., Daneshmand, Mani A, Schroder, Jacob N., Chiang, Yuting, Lee, Franklin H., Brown, Zachary D., Nevo, Adam, Watson, Michael J., Rowell, Trevelyn, Paul, Sally, Lezberg, Paul, Walczak, Richard, Bowles, Dawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541710/
https://www.ncbi.nlm.nih.gov/pubmed/31142753
http://dx.doi.org/10.1038/s41598-019-43737-y

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