Integrative Data Mining, Scaffold Analysis, and Sequential Binary Classification Models for Exploring Ligand Profiles of Hepatic Organic Anion Transporting Polypeptides

[Image: see text] Hepatocellular organic anion transporting polypeptides (OATP1B1, OATP1B3, and OATP2B1) are important for proper liver function and the regulation of the drug elimination process. Understanding their roles in different conditions of liver toxicity and cancer requires an in-depth inv...

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Detalles Bibliográficos
Autores principales: Türková, Alžběta, Jain, Sankalp, Zdrazil, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541895/
https://www.ncbi.nlm.nih.gov/pubmed/30372058
http://dx.doi.org/10.1021/acs.jcim.8b00466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541895/
https://www.ncbi.nlm.nih.gov/pubmed/30372058
http://dx.doi.org/10.1021/acs.jcim.8b00466

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