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FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors – implications for therapy of luminal breast cancer

Stromal stimuli mediated by growth factor receptors, leading to ligand-independent activation of steroid hormone receptors, have long been implicated in development of breast cancer resistance to endocrine therapy. Mutations in fibroblast growth factor receptor (FGFR) genes have been associated with...

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Detalles Bibliográficos
Autores principales: Piasecka, Dominika, Braun, Marcin, Kitowska, Kamila, Mieczkowski, Kamil, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542018/
https://www.ncbi.nlm.nih.gov/pubmed/31142340
http://dx.doi.org/10.1186/s13046-019-1236-6