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Elucidating the endogenous synovial fluid proteome and peptidome of inflammatory arthritis using label-free mass spectrometry

BACKGROUND: Inflammatory arthritis (IA) is an immunological disorder in which loss of immune tolerance to endogenous self-antigens perpetuates synovitis and eventual destruction of the underlying cartilage and bone. Pathological changes in the joint are expected to be represented by synovial fluid (...

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Detalles Bibliográficos
Autores principales: Mahendran, Shalini M., Keystone, Edward C., Krawetz, Roman J., Liang, Kun, Diamandis, Eleftherios P., Chandran, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542032/
https://www.ncbi.nlm.nih.gov/pubmed/31160890
http://dx.doi.org/10.1186/s12014-019-9243-3