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Androgen promotes differentiation of PLZF(+) spermatogonia pool via indirect regulatory pattern

BACKGROUND: Androgen plays a pivotal role in spermatogenesis, accompanying a question how androgen acts on germ cells in testis since germ cells lack of androgen receptors (AR). Promyelocytic leukemia zinc-finger (PLZF) is essential for maintenance of undifferentiated spermatogonia population which...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Li, Jinmei, Xu, Wei, Xia, Qin, Gu, Yunzhao, Song, Weixiang, Zhang, Xiaoyu, Yang, Yang, Wang, Wei, Li, Hua, Zou, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542041/
https://www.ncbi.nlm.nih.gov/pubmed/31142324
http://dx.doi.org/10.1186/s12964-019-0369-8