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E2F1 germline copy number variations and melanoma susceptibility

BACKGROUND: Melanoma is an aggressive type of skin cancer whose aetiology remains elusive as both environmental and genetic factors can contribute to its development. Recent studies have demonstrated the existence of multiple copies of E2F1 gene in melanoma specimens which could explain the deregula...

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Detalles Bibliográficos
Autores principales: Rocca, Maria Santa, Benna, Clara, Mocellin, Simone, Rossi, Carlo Riccardo, Msaki, Aichi, Di Nisio, Andrea, Opocher, Giuseppe, Foresta, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542053/
https://www.ncbi.nlm.nih.gov/pubmed/31142321
http://dx.doi.org/10.1186/s12967-019-1933-0