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Transmembrane-4 L-six family member-1 (TM4SF1) promotes non-small cell lung cancer proliferation, invasion and chemo-resistance through regulating the DDR1/Akt/ERK-mTOR axis

BACKGROUND: Tumor chemo-resistance is a hallmark of malignant tumors as well as the major cause of poor survival rates in lung cancer. Transmembrane-4 L-six family member-1 (TM4SF1), an antigen that serves as an oncogene, mainly affects tumor invasion and metastasis. We investigated the roles of TM4...

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Detalles Bibliográficos
Autores principales: Ye, Lin, Pu, Chunyun, Tang, Jun, Wang, Yan, Wang, Can, Qiu, Zhu, Xiang, Tingxiu, Zhang, Yunmei, Peng, Weiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542073/
https://www.ncbi.nlm.nih.gov/pubmed/31142317
http://dx.doi.org/10.1186/s12931-019-1071-5