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Novel GTF2I–PDGFRB and IKZF1–TYW1 fusions in pediatric leukemia with normal karyotype

BACKGROUND: Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance. Nevertheless, from one-fourth to half of newly diagnosed ALL patients have no visible chromosomal changes detectable by G-banding analysis a...

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Detalles Bibliográficos
Autores principales: Panagopoulos, Ioannis, Brunetti, Marta, Stoltenberg, Margrethe, Strandabø, Rønnaug A. U., Staurseth, Julie, Andersen, Kristin, Kostolomov, Ilyá, Hveem, Tarjei S., Lorenz, Susanne, Nystad, Tove Anita, Flægstad, Trond, Micci, Francesca, Heim, Sverre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542082/
https://www.ncbi.nlm.nih.gov/pubmed/31161074
http://dx.doi.org/10.1186/s40164-019-0136-y