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Adenomatous Polyposis Coli Gene Mutations in 22 Chinese Pedigrees with Familial Adenomatous Polyposis

BACKGROUND: Familial adenomatous polyposis (FAP), which has a very high tendency of progression to colorectal cancer, is mainly caused by mutations of the adenomatous polyposis coli (APC) gene. This study systematically screened the APC mutations and observed the correlation of APC mutations with cl...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Zhang, Zhao, Li, Yuwei, Xu, Chen, Yu, Yongjun, Li, Mingsen, Chen, Chao, Zhang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542301/
https://www.ncbi.nlm.nih.gov/pubmed/31113927
http://dx.doi.org/10.12659/MSM.913911