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Interventional cohort study of prolonged use (>72 hours) of paracetamol in neonates: protocol of the PARASHUTE study

INTRODUCTION: Anticipated or actual pain in neonates results in use of paracetamol for prolonged pain relief in many neonatal intensive care units. Clinical trials examining safety of paracetamol exposure in neonates have been of short duration (1–3 days) and hepatic biomarkers and paracetamol metab...

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Detalles Bibliográficos
Autores principales: Haslund-Krog, Sissel Sundell, Hertel, Steen, Dalhoff, Kim, Poulsen, Susanne, Christensen, Ulla, Wilkins, Diana, van den Anker, John, Brink Henriksen, Tine, Holst, Helle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542439/
https://www.ncbi.nlm.nih.gov/pubmed/31206077
http://dx.doi.org/10.1136/bmjpo-2018-000427