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Interventional cohort study of prolonged use (>72 hours) of paracetamol in neonates: protocol of the PARASHUTE study
INTRODUCTION: Anticipated or actual pain in neonates results in use of paracetamol for prolonged pain relief in many neonatal intensive care units. Clinical trials examining safety of paracetamol exposure in neonates have been of short duration (1–3 days) and hepatic biomarkers and paracetamol metab...
Autores principales: | Haslund-Krog, Sissel Sundell, Hertel, Steen, Dalhoff, Kim, Poulsen, Susanne, Christensen, Ulla, Wilkins, Diana, van den Anker, John, Brink Henriksen, Tine, Holst, Helle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542439/ https://www.ncbi.nlm.nih.gov/pubmed/31206077 http://dx.doi.org/10.1136/bmjpo-2018-000427 |
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