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The immunomodulatory role of tumor Syndecan-1 (CD138) on ex vivo tumor microenvironmental CD4(+) T cell polarization in inflammatory and non-inflammatory breast cancer patients

Herein, we aimed to identify the immunomodulatory role of tumor Syndecan-1 (CD138) in the polarization of CD4(+) T helper (Th) subsets isolated from the tumor microenvironment of inflammatory breast cancer (IBC) and non-IBC patients. Lymphocytes and mononuclear cells isolated from the axillary tribu...

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Detalles Bibliográficos
Autores principales: Saleh, Moshira Ezzat, Gadalla, Ramy, Hassan, Hebatallah, Afifi, Ahmed, Götte, Martin, El-Shinawi, Mohamed, Mohamed, Mona Mostafa, Ibrahim, Sherif Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542534/
https://www.ncbi.nlm.nih.gov/pubmed/31145753
http://dx.doi.org/10.1371/journal.pone.0217550