Parameter estimation and mathematical modeling for the quantitative description of therapy failure due to drug resistance in gastrointestinal stromal tumor metastasis to the liver

In this work we develop a general mathematical model and devise a practical identifiability approach for gastrointestinal stromal tumor (GIST) metastasis to the liver, with the aim of quantitatively describing therapy failure due to drug resistance. To this end, we have modeled metastatic growth and...

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Detalles Bibliográficos
Autores principales: Cumsille, Patricio, Godoy, Matías, Gerdtzen, Ziomara P., Conca, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542538/
https://www.ncbi.nlm.nih.gov/pubmed/31145737
http://dx.doi.org/10.1371/journal.pone.0217332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542538/
https://www.ncbi.nlm.nih.gov/pubmed/31145737
http://dx.doi.org/10.1371/journal.pone.0217332

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