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Ventral hippocampal projections to the medial prefrontal cortex regulate social memory

Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the Mecp2 knockout mouse model of the autism spectrum disorder Rett syndrome, which has deficits in so...

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Detalles Bibliográficos
Autores principales: Phillips, Mary L, Robinson, Holly Anne, Pozzo-Miller, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542587/
https://www.ncbi.nlm.nih.gov/pubmed/31112129
http://dx.doi.org/10.7554/eLife.44182