TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells

The aberrant activation of the ERG oncogenic pathway due to the TMPRSS2-ERG gene fusion is the major event that contributes to prostate cancer (PCa) development. However, the critical downstream effectors that can be therapeutically targeted remain to be identified. In this study, we have found that...

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Detalles Bibliográficos
Autores principales: Zhou, Feng, Gao, Shuai, Han, Dong, Han, Wanting, Chen, Sujun, Patalano, Susan, Macoska, Jill A., He, Housheng Hansen, Cai, Changmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542710/
https://www.ncbi.nlm.nih.gov/pubmed/30718921
http://dx.doi.org/10.1038/s41388-019-0730-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542710/
https://www.ncbi.nlm.nih.gov/pubmed/30718921
http://dx.doi.org/10.1038/s41388-019-0730-9

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