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TMPRSS2-ERG activates NO-cGMP signaling in prostate cancer cells
The aberrant activation of the ERG oncogenic pathway due to the TMPRSS2-ERG gene fusion is the major event that contributes to prostate cancer (PCa) development. However, the critical downstream effectors that can be therapeutically targeted remain to be identified. In this study, we have found that...
Autores principales: | Zhou, Feng, Gao, Shuai, Han, Dong, Han, Wanting, Chen, Sujun, Patalano, Susan, Macoska, Jill A., He, Housheng Hansen, Cai, Changmeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542710/ https://www.ncbi.nlm.nih.gov/pubmed/30718921 http://dx.doi.org/10.1038/s41388-019-0730-9 |
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