PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells

PRRX1 is a homeodomain transcriptional factor, which has two isoforms, PRXX1A and PRRX1B. The PRRX1 isoforms have been demonstrated to be important in pancreatic cancer, especially in the regulation of epithelial-to-mesenchymal transition (EMT) in Pancreatic Ductal Adenocarcinoma (PDAC) and of mesen...

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Detalles Bibliográficos
Autores principales: Marchand, Benoît, Pitarresi, Jason R., Reichert, Maximilian, Suzuki, Kensuke, Laczkó, Dorottya, Rustgi, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542713/
https://www.ncbi.nlm.nih.gov/pubmed/30705403
http://dx.doi.org/10.1038/s41388-019-0725-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542713/
https://www.ncbi.nlm.nih.gov/pubmed/30705403
http://dx.doi.org/10.1038/s41388-019-0725-6

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