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PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells
PRRX1 is a homeodomain transcriptional factor, which has two isoforms, PRXX1A and PRRX1B. The PRRX1 isoforms have been demonstrated to be important in pancreatic cancer, especially in the regulation of epithelial-to-mesenchymal transition (EMT) in Pancreatic Ductal Adenocarcinoma (PDAC) and of mesen...
Autores principales: | Marchand, Benoît, Pitarresi, Jason R., Reichert, Maximilian, Suzuki, Kensuke, Laczkó, Dorottya, Rustgi, Anil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542713/ https://www.ncbi.nlm.nih.gov/pubmed/30705403 http://dx.doi.org/10.1038/s41388-019-0725-6 |
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