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A novel bispecific c-MET/CTLA-4 antibody targetting lung cancer stem cell-like cells with therapeutic potential in human non-small-cell lung cancer

A novel paradigm in tumor biology suggests that non-small-cell lung cancer (NSCLC) growth is driven by lung cancer stem cell (LCSC) like cells, but t here are still not any effective strategies to remove LCSCs. The bispecific antibody (BsAb) is a novel antibody, which can target two different antige...

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Detalles Bibliográficos
Autores principales: Li, Jian-feng, Niu, Yuan-yuan, Xing, Yan-li, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542762/
https://www.ncbi.nlm.nih.gov/pubmed/29187584
http://dx.doi.org/10.1042/BSR20171278