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Overcoming chemotherapy resistance via simultaneous drug-efflux circumvention and mitochondrial targeting
Multidrug resistance (MDR) has been considered as a huge challenge to the effective chemotherapy. Therefore, it is necessary to develop new strategies to effectively overcome MDR. Here, based on the previous research of N-(2-hydroxypropyl)methacrylamide (HPMA) polymer–drug conjugates, we designed an...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542785/ https://www.ncbi.nlm.nih.gov/pubmed/31193791 http://dx.doi.org/10.1016/j.apsb.2018.11.005 |