Combined obeticholic acid and apoptosis inhibitor treatment alleviates liver fibrosis

Obeticholic acid (OCA), the first FXR-targeting drug, has been claimed effective in the therapy of liver fibrosis. However, recent clinical trials indicated that OCA might not be effective against liver fibrosis, possibly due to the lower dosage to reduce the incidence of the side-effect of pruritus...

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Detalles Bibliográficos
Autores principales: Zhou, Jiyu, Huang, Ningning, Guo, Yitong, Cui, Shuang, Ge, Chaoliang, He, Qingxian, Pan, Xiaojie, Wang, Guangji, Wang, Hong, Hao, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542786/
https://www.ncbi.nlm.nih.gov/pubmed/31193776
http://dx.doi.org/10.1016/j.apsb.2018.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542786/
https://www.ncbi.nlm.nih.gov/pubmed/31193776
http://dx.doi.org/10.1016/j.apsb.2018.11.004

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