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The metabolites NADP(+) and NADPH are the targets of the circadian protein Nocturnin (Curled)

Nocturnin (NOCT) is a rhythmically expressed protein that regulates metabolism under the control of circadian clock. It has been proposed that NOCT deadenylates and regulates metabolic enzyme mRNAs. However, in contrast to other deadenylases, purified NOCT lacks the deadenylase activity. To identify...

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Detalles Bibliográficos
Autores principales: Estrella, Michael A., Du, Jin, Chen, Li, Rath, Sneha, Prangley, Eliza, Chitrakar, Alisha, Aoki, Tsutomu, Schedl, Paul, Rabinowitz, Joshua, Korennykh, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542800/
https://www.ncbi.nlm.nih.gov/pubmed/31147539
http://dx.doi.org/10.1038/s41467-019-10125-z