Cargando…

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy

FAM134B/RETREG1 is a selective ER-phagy receptor that regulates the size and shape of the endoplasmic reticulum. The structure of its reticulon-homology domain (RHD), an element shared with other ER-shaping proteins, and the mechanism of membrane shaping remain poorly understood. Using molecular mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhaskara, Ramachandra M., Grumati, Paolo, Garcia-Pardo, Javier, Kalayil, Sissy, Covarrubias-Pinto, Adriana, Chen, Wenbo, Kudryashev, Mikhail, Dikic, Ivan, Hummer, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542808/
https://www.ncbi.nlm.nih.gov/pubmed/31147549
http://dx.doi.org/10.1038/s41467-019-10345-3