Cargando…

Linking demyelination to compound action potential dispersion with a spike-diffuse-spike approach

To establish and exploit novel biomarkers of demyelinating diseases requires a mechanistic understanding of axonal propagation. Here, we present a novel computational framework called the stochastic spike-diffuse-spike (SSDS) model for assessing the effects of demyelination on axonal transmission. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Naud, Richard, Longtin, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542900/
https://www.ncbi.nlm.nih.gov/pubmed/31147800
http://dx.doi.org/10.1186/s13408-019-0071-6