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Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type
Acid-sensing ion channels (ASICs) are neuronal Na(+)-permeable ion channels that are activated by extracellular acidification and are involved in fear sensing, learning, neurodegeneration after ischemia, and in pain sensation. We have recently found that the human ASIC1a (hASIC1a) wild type (WT) clo...
Autores principales: | Vaithia, Anand, Vullo, Sabrina, Peng, Zhong, Alijevic, Omar, Kellenberger, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542941/ https://www.ncbi.nlm.nih.gov/pubmed/31178694 http://dx.doi.org/10.3389/fnmol.2019.00133 |
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