Cargando…

Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors

Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory effect of the tetracyclic antidepressant mianseri...

Descripción completa

Detalles Bibliográficos
Autores principales: Sacre, Sandra, Jaxa-Chamiec, Albert, Low, Caroline M. R., Chamberlain, Giselle, Tralau-Stewart, Cathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542943/
https://www.ncbi.nlm.nih.gov/pubmed/31244825
http://dx.doi.org/10.3389/fimmu.2019.01167