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Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors
Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory effect of the tetracyclic antidepressant mianseri...
Autores principales: | Sacre, Sandra, Jaxa-Chamiec, Albert, Low, Caroline M. R., Chamberlain, Giselle, Tralau-Stewart, Cathy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542943/ https://www.ncbi.nlm.nih.gov/pubmed/31244825 http://dx.doi.org/10.3389/fimmu.2019.01167 |
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